For more information, call the ATSDR Information Center at 1-800-232-4636. The factors most strongly associated with the occurrence of symptoms were drinking tap water (OR = 7.8), exposure to vapors from the basement (OR = 10.4) and eating foods prepared with tap water after the occurrence of the contamination (OR = 8.6). Manolis Kogevinas. 2001, 58: 95-102. Many animals and people were also seen fainting on the road. On December 10, 1999, residents of a neighborhood at Castellón, NE Spain informed the local authorities that drinking tap water had a strong solvent-type smell and produced nausea and various other health symptoms when consumed. Although there aren't many studies that have been conducted on the effect of styrene gas. Biological monitoring of Chemical Exposure in the Workplace. statement and J Epidemiol Biostat. Environ Health 2, 6 (2003). The plastic plant was being prepped to re-open after the entire nation had been under lockdown due to the coronavirus pandemic. Multiple central and peripheral acute nervous system effects have been described at levels of about 100 ppm but some neurological symptoms and color vision impairment may also appear at much lower levels [4–6]. Similar exposures have been described in workers but not in subjects exposed at their residence. This is also suggested by the relation observed between symptoms and consumption of water and of food prepared with water. Symptoms were reported by 46 persons (attack rate 55 %). The effects of exposure to any hazardous substance depend on the dose, the duration, how you are exposed, personal traits and habits, and whether other chemicals are present. Given the very high levels measured in water, it could be expected that extensive exposure of the skin and the mucosa occurred. About 80-100 people have been hospitalised and at least 10 persons, including two senior citizens and an 8-year-old girl, have died, reports Times of India. 1969, 19: 55-85. MA and PGA were not detected in the urine samples collected at day 5. Stata Reference Manual. Below are the links to the authors’ original submitted files for images. We studied subjective health symptoms in a population accidentally exposed to high styrene concentrations in drinking tap water. Cite this article. D indicates the water pump for Tank B. In addition to the irritative effects to the eye, skin and respiratory tract frequently reported in workers, various gastrointestinal type symptoms were observed in this population that ingested highly contaminated water. The contamination occurred during the reparation of a water tank. Article Physicians attended nine subjects and confirmed irritation type symptoms but none of the subjects were hospitalized. The two major effects of acute exposure to styrene in humans include irritation (both skin and respiratory tract) and central nervous system (CNS). Dr D Raghunatha Rao, former director of Homi Bhabha Cancer Hospital and Research Centre, on Styrene gas leak and its effect on human beings, explained to The News Meter, "Acute (short-term) exposure to styrene in humans results in mucous membrane and eye irritation, and gastrointestinal effects. A questionnaire on subjective symptoms was administered to 84 out of 93 persons living in the apartments at the time of the accident. Samples were analyzed by gas chromatography/mass spectrometry. This accidental contamination led to very high styrene concentrations in water and was related to a high prevalence of subjective symptoms of the eyes, respiratory tract and skin. The possibility of a contamination was suggested due to a communication in the air environment of the two tanks. People living near the facility and those affected by the gas leak said they were facing difficulties in breathing, rashes, irritation of the throat, sour eyes, vomiting. 1994, 60: 1-560. Bond J: Review of the toxicology of styrene. Environmental Health The taste threshold concentration in water is around 0.7 mg/L .