benzyl acetate molecular weight


The rat acute oral LD50 for the oil is 400 mg/kg (Opdyke 1974), approximately equivalent to 1 oz of pennyroyal oil being fatal when ingested by an adult (Anon 1978). We further analyzed the trichomes content of ssu-GgFPS transgenic plants by gas chromatography–mass spectrometry (GC–MS). General structures of three classes of bifunctional QM precursors. Products are for research use only. Nor were other putative substrates, such as p-coumaroyl- and feruloyl-CoAs examined either. * When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online). Irradiation of 31d at 360 nm led to efficient DNA ICL formation. b–fValues with the same superscripts within a column are tentatively assigned and may be interchangeable. In a study conducted by Abdo (1986), groups of 50 mice of each sex received 0,500, or 1,000 mg/ kg benzyl acetate in corn oil by gavage, 5 days per week for 103 weeks. Scheme 6.14. 6 represent the π[Ph/(CH3COOCH2)H]. Users are advised to carry out their own tests and experiments to establish suitability of our products. The rats were fed the test substance in feed containing 0, 300, 600 or 1200mg/kg bw/day benzyl acetate daily over a two year period. Under the conditions of this study, there was no evidence of carcinogenic activity of benzyl acetate in male or female B6C3F1 mice following oral administration of the test substance at 33, 100 and 300mg/kg bw/day over 2 years. BENZYL DIMETHYL PHOSPHONOACETATE. These controls were sacrificed early in the study (weeks 53-55 for mice) as a result of a program wide decision that vehicle controls are more appropriate than untreated controls for interpreting the results of gavage studies.Under the conditions of these studies, for male and female B6C3F1 mice there was some evidence of carcinogenicity in that benzyl acetate caused increased incidences of hepatocellular adenomas and squamous cell neoplasms of the forestomach.The carcinogenic potential of Benzyl Acetate is inconclusive based on the results of this study. Artificial Jasmine & Other Perfumes, For additional information regarding our products or for information concerning current specifications, please contact our Technical Service. Scheme 6.10. Other test substrates such as cinnamyl alcohol (284), sinapyl alcohol (94), octanol (302), and geraniol (303) were processed ∼2–4 times slower, with activities 30–60 times lower being observed using p-coumaryl alcohol (199) and 2-phenylethanol (296) at the same substrate concentrations. 6.5. Survival of all exposed mice, except the 300mg/kg bw/day females was similar to that of the control groups. Table 4.3 summarizes the 1H NMR data (δ and J when quoted) of saraines 1–3 (1–3) according to Cimino and coworkers.9,12, Table 4.4 summarizes the 1H NMR data (δ and J when quoted) of isosaraines 1–3 (4–6) according to Cimino and coworkers.12,13,15. The trichome content was extracted using methanol:water (1:3, v/v). The elimination half-lives of some essential oil constituents are shown in Table 4.8. If these figures are typical, wintergreen oil is some 1.5–4.5 times more toxic to humans on a bodyweight basis than it is to rodents, and data showing dietary methyl salicylate to be non-toxic to rats at 700–2100 mg/kg should not be extrapolated directly to humans (Packman et al 1961). As 400 nm irradiation is biocompatible, compound 29a has the potential to be used as DNA cross-linking agent for cancer treatment. We are an ISO 9001:2015, ISO 14001:2015, ISO 45001:2018 Halal India and Kosher certified company and we also have DUNS Registration. As shown in Fig. Benzyl cinnamate 24.0%, benzyl acetate 16.5%, 1,8-cineole 13.0%, linalyl acetate 11.5%, and linalool 8.5% have been reported as constituents of this oil (Sinha et al 1977, cited in Burfield 2000 p264). Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. Under the conditions of this study, there was no evidence of carcinogenic activity of benzyl acetate in male or female B6C3F1 mice following oral administration of the test substance at 33, 100 and 300mg/kg bw/day over 2 years. This will enable us to investigate its cause and server you better. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments. The log P value of an experimental amide-type Hill reaction inhibitor (Shimizu et al., 1988) was derived as follows: The second and third terms together express the Δ log P value between the OPh and CH2Ph compounds having the XCH2CONH2 structure, which is actually equivalent to Δπ = π[OPh/H(CH2CONH2)] − π[CH2Ph/H(CH2CONH2)]. 1 Structures Expand this section. Vapor or mist is irritating to the eyes, mucous membrane and upper respiratory tract. All such risk are assumed by the user. Krishna Chemicals was established decades back in 1983. Close Find out more on how we use cookies. Scheme 6.16. Different leaving groups were attached and their reactivities were tested [37,44–46]. Next day delivery by 10:00 a.m. Order now. This website uses cookies to ensure you get the best experience on our websites. We use cookies to help provide and enhance our service and tailor content and ads. (USCG, 1999). Photoirradiation of 29b led to efficient DNA ICL formation. Similar to most other esters, it possesses a sweet and pleasant aroma, owing to which, it finds applications in personal hygiene and health care products. Cyclophosphamide Monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA, shown to crosslink DNA, causing strand breakage and inducing mutations. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. In Table 4.5 is given a comparison of 13C and 1H NMR data for saraines A–C (7–9) published by Cimino in 1996.17 13C NMR (for 7–9)16 and 1H NMR (for 7) data11 have been reported before, but no JH,H were quoted in any of these references. Using RNAi for the so-called PhCAAT, their levels were also adversely affected as noted above. Calculate the dilution required to prepare a stock solution. 9,13,15 those concerning isosaraine 3 (6) and also the latest data for saraine 3 (3). 6A shows the relative amounts of FPP detected in the trichomes of untransformed plants and ssu-GgFPS transgenics (n = 3). We have achieved several milestones under the expert guidance of Mr. Mehul Shah, 4 Spectral Information Expand this section. A variety of QM precursors have been developed to induce DNA ICL formation. Histopathology of Preclinical Toxicity Studies (Fourth Edition). Values are interchangeable within a column. It was then said that the linkages of the alkyl chains at C-1 and C-9 (see numbering in Figure 4.6) could be reversed and that their length could vary. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. 2 acceptable studies are available. Food Chem. C10H16N2O2 c10h16n2o2. QM formation induced by photoirradiation has wide applications in biological systems since no coreagent is needed. Photoinduced bifunctional prototype QM formation. Method for preparing in vivo formulation:Take Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. 1272/2008. EYES: First check the victim for contact lenses and remove if present. benzyl 2-(dimethoxyphosphoryl)acetate. Throughout the 2 -year study, the mean body weights of 100 and 300mg/kg bw/day males and females were 2 to 14% lower than those of the control groups. Although cases of human poisoning permit a comparison of median lethal dose, they do not tell us what a safe dose is. © Copyright 2013 Selleck Chemicals. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. Various ketones are also produced during fermentation. The most abundant alcohols are 1-propanol, 2-methyl-1-propanol, 2-methyl-1-butanol, and 3-methyl-1-butanol. Scheme 6.11. For example, when cinnamaldehyde was given with corn oil by gavage to rats, doses of 940 mg/kg/day produced almost 100% mortality, while a similar dose in feed caused no deaths (Hébert et al 1994). Figure 4. They are given in good faith solely for the consideration of the users. Ribavirin (NSC-163039, ICN-1229, RTCA, Tribavirin), a synthetic guanosine analogue, possesses a broad spectrum of activity against DNA and RNA viruses. Several strategies were used to extend the conjugation of the system. Alternate acyl donors were apparently also not tested during the preliminary characterization of the basil acyltransferase. drug pre-dissolved in μL DMSO (Master liquid concentration Molecular Weight: 150.17. R.W.J. To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'. The few exceptions, such as hexanols, benzyl alcohol, and 2-phenylethanol, are usually derived from the raw material. Under the conditions of this study, there was no evidence of carcinogenic activity of benzyl acetate in male or female F344/N rats following oral administration of the test substance at 300mg/kg bw/day, 600 mg/kg bw/day or 1200 mg/kg bw/day over 2 years. Under the conditions of this study, there was no evidence of carcinogenic activity of benzyl acetate in male or female F344/N rats following oral administration of the test substance at 300mg/kg bw/day, 600mg/kg bw/day or 1200mg/kg bw/day over 2 years.

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